Magnesium glycinate and magnesium oxide are both forms of magnesium supplements, but they differ significantly in their bioavailability and potential side effects. The disparity arises from the different molecules to which the magnesium is bound. Magnesium glycinate is chelated with glycine, an amino acid, while magnesium oxide is bound to oxygen.
The form of magnesium dictates how well it is absorbed in the body. Magnesium glycinate typically exhibits superior absorption compared to magnesium oxide. This enhanced absorption translates to more magnesium reaching the bloodstream and cells, making it more effective for addressing magnesium deficiencies. Conversely, magnesium oxide’s lower absorption rate means that a larger proportion remains in the intestines.
